Pembuatan Natrium Karboksimetil Selulosa (Na CMC) Dari Batang Rumput Gajah (Pennisetum purpureum Schumach)
DOI:
https://doi.org/10.52689/higea.v4i2.65Keywords:
sodium carbocxymetil cellulose, cellulose, stems elephant grassAbstract
A study on the preparation of sodium carboxymethil cellulose (Na-CMC) from celulose powder that was isolated from the stems elephant grass (Pennisetum purpureum Schumach) has been performed. Cellulose was purified using 17.5% of sodium hydroxide solution, then bleach, dried and crushed to obtain alpha cellulose. Alfa cellulose was eterified with sodium chloroacetat resulting sodium carboxymethyl cellulose, furthermore characterized: organoleptic, losses on drying, chemical identification, pH test and test with fourier transform infrared (FT-IR). The results showed that of 300 g stems elephant grass yield alpha cellulose as much as 92,.54 g and 25 g of alpha cellulose produced Na-CMC as 16.92 g. Based on the characterization made Na-CMC and Na-CMC Merck® meet Indonesian Pharmacopoeia 3th edition requirement.References
Departemen Kesehatan RI, 1979, Farmakope Indonesia (Edisi 3), Jakarta: Departemen Kesehatan Republik Indonesia.
He, X., Wu, S., Fu, D., and Ni, J., 2008, Preparation of Sodium Carboxymethyl Cellulose from Paper Sludge. Journal of Chemical Technology and Biotechnology , 84: 427-434.
Ohwoavworhua, F.O., Adelakun, T.A., dan Okhamafe A.O., 2009, Processing Pharnaceutical Grade Microcryistalline Cellulose from Groundnut Husk: Extraction Methods and Characterization, International Journal of Green Pharmacy, 70: 97-104.
Rowe, R.C., Sheskay, P.J., Owen, S.C., 2006, Handbook of Pharmaceutical Excipients, London: Pharmaceutical Press.
Sanderson , M . A., and Paul, R. A., 2008, Perennial Forages as Second Generation Bioenergy Crop,. International Journal Of Molecur Sciences, 9: 768 – 788.
Sari, K.., 2009, Purifikasi Bioentanol dari Rumput Gajah dengan Destilasi Batch. Surabaya: Universitas Pembangunan Nasional.
Sjostrom, E., 1998, Kimia Kayu: Proses Dasar dan Penggunaannya, terjemahan Hardjono Sastrohamidjono, Yogyakarta: Gajah Mada University press.
Ye, D., Montane, D., Farriol, X., 2005, Preparation and Characterization of Methylcellulose form Annual Cardoon and Juvenile Eucalyptus, Journal of Carbohidrat Polymer, 6: 446-454.
